Serous Retinopathy Associated With Combination MEK and Fibroblast Growth Factor Receptor Inhibitor
نویسندگان
چکیده
Purpose: To present a case of chemotherapy regimen combining fibroblast growth factor receptor (FGFR) and mitogen-activated protein kinase (MEK) inhibitor leading to serous retinopathy. Methods: A retrospective chart review single was performed. Results: 67-year-old man with pancreatic prostate cancer developed bilateral multifocal pockets subretinal fluid while on an experimental MEK (trametinib) FGFR (erdafitinib). Conclusions: Given that lies upstream the signaling pathway, retinal toxicity may be more severe common FGFR–MEK combination therapy. Future studies are necessary guide ophthalmic surveillance.
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ژورنال
عنوان ژورنال: Journal of vitreoretinal diseases
سال: 2023
ISSN: ['2474-1264', '2474-1272']
DOI: https://doi.org/10.1177/24741264231163393